The role of CYP2D6 and ABCB1 pharmacogenetics in drug-naïve patients with first-episode schizophrenia treated with risperidone.
Eur J Clin Pharmacol. 2010 Nov;66(11):1109-17
Authors: Jovanović N, Božina N, Lovrić M, Medved V, Jakovljević M, Peleš AM
To evaluate the role of cytochrome 450 2D6 (CYP2D6) and ABCB1 variants on plasma risperidone concentrations and treatment response in 83 drug-naive patients experiencing a first episode of psychosis.
PMID: 20563569 [PubMed - indexed for MEDLINE]