Pharmacogenetics of toxic epidermal necrolysis.
Expert Opin Pharmacother. 2010 Sep;11(13):2153-62
Authors: Lee MT, Hung SI, Wei CY, Chen YT
Toxic epidermal necrolysis (TEN) and Stevens-Johnson Syndrome (SJS) are two of the most severe drug-induced cutaneous reactions. Advances in genome technologies have allowed researchers to identify genetic markers associated with this drug-associated event and these have provided a potential tool for prevention.
PMID: 20536296 [PubMed - indexed for MEDLINE]